THz-Biosensing

Biosensing is applying sensors to characterize biomolecules such as DNA or Proteins. A numerous amount of biomolecules shows characteristic properties in the THz-regime. Suitable sensors are excited with THz-pulses or –radiation to determine the molecules’ material properties.
One application of great interest is the determination of DNA-strands based on the binding state. Nowadays the commom method is the expensive and time-consuming fluorescent labelling. Biochips would require deposition of the (small amount of) material on the chip only. The permittivity of the sample material then indicates the binding state. This process is not only simpler, it also allows the usage of the material after the diagnosis since it is not contaminated with a fluorescent label.

Projects

ESSENCE

Ultrasensitive marker-free biomolecular THz-detection for tumor related analytics: PCR-free sensitivity, biomolecular extension and biological relevance.

The project is part of the DFG (German Research Foundation) founded SPP 1857 ESSENCE (Electromagnetic sensors for life sciences). Further information is available on the project website.

EIFFEL

BMFB-Project: "Early invasive fungal infection detection with Terahertz sensor systems"

Project Website

Completed Projects

MOSES

EU-Project: » "Research School on Multi-Modal Sensor Systems for Environmental Exploration" (MOSES)

Project Website

DNA-Detektor

Industry Research Project: » "DNA-Detektor"

Teranova

EU Project: » "Terahertz Sensing and Imaging Systems for Biotechnology, Healthcare, Security and Process Monitoring" (Teranova)

Project Website

IRTeN

ARO Project: » "Integrated resonant THz nanosensing probes" (IRTeN)

Metamorphose

EU Network of Excellence: » "Metamaterials Organized for radio, millimeter wave, and Photonic Superlattice Engineering" (Metamorphose)

Project Website